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Symptom

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Expert Definition

Understanding This Symptom

Medical Definition

Subject Matter Expert Verified

Glaucoma is an eye disease where elevated intraocular pressure damages the optic nerve, leading to progressive peripheral vision loss and potentially blindness if untreated.

It is often called the "silent thief of sight" because vision loss occurs gradually and irreversibly.

The condition affects over 80 million people worldwide and is the leading cause of irreversible blindness.

Primary open-angle glaucoma is the most common form, accounting for about 90% of cases, while angle-closure glaucoma is less common but more acute and dangerous.

Quick Facts

Expert-reviewed by medical professionals
Based on current medical research
Updated for 2026 standards

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Healthy State

What Optimal Health Looks Like

Understanding how your body functions when healthy helps identify dysfunction

A healthy eye maintains precise intraocular pressure (IOP) through a delicate balance between aqueous humor production and drainage.

The ciliary body in the eye produces aqueous humor, a clear fluid that circulates through the anterior chamber and drains primarily through the trabecular meshwork into Schlemm's canal.

This fluid nourishes the lens and cornea and removes metabolic waste.

The optic nerve, composed of over 1 million retinal ganglion cell axons, transmits visual information from the retina to the brain.

Healthy Function

Your body is designed to maintain balance and self-regulate

Optimal Range
Development Process

How This Develops

1

Open-angle glaucoma - The drainage angle remains open but the trabecular meshwork becomes less efficient, causing gradual aqueous humor outflow obstruction and progressive IOP elevation

2

Angle-closure glaucoma - The iris physically blocks the drainage angle, causing rapid IOP elevation

Understanding the mechanism helps us target the root cause rather than just treating symptoms.

Cost of Waiting

What Happens If Left Untreated

Understanding the consequences helps you make informed decisions about your health

Short-Term Consequences

Days to weeks

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Time Matters

Don't wait for symptoms to worsen. Early intervention leads to better outcomes.

Common Questions

Frequently Asked Questions

Expertise Behind This Guide

Evidence-Based Information

Dr. Hafeel Afsar, DHA Licensed Integrative Medicine

References & Further Reading

Weinreb RN, Aung T, Medeiros FA. The Pathophysiology and Treatment of Glaucoma. JAMA. 2014;311(18):1901-1911. PMID: 24825645 - Comprehensive review of glaucoma pathophysiology and treatment approaches.
Leske MC, Heijl A, Hussein M, et al. Factors for Glaucoma Progression and the Effect of Treatment: The Early Manifest Glaucoma Trial. Arch Ophthalmol. 2003;121(1):48-56. PMID: 12523882 - Landmark study on glaucoma progression risk factors.
Kass MA, Heuer DK, Higginbotham EJ, et al. The Ocular Hypertension Treatment Study: A Randomized Trial Determines That Topical Ocular Hypotensive Medication Delays or Prevents the Onset of Primary Open-Angle Glaucoma. Arch Ophthalmol. 2002;120(6):701-713. PMID: 12049574 - Critical trial on ocular hypertension treatment.
Quigley HA, Broman AT. The Number of People with Glaucoma Worldwide in 2010 and 2020. Br J Ophthalmol. 2006;90(3):262-267. PMID: 16488940 - Epidemiology of glaucoma globally.
Lee DA, Higginbotham EJ. Glaucoma and its Treatment: A Review. Am J Health Syst Pharm. 2005;62(7):691-699. PMID: 15790790 - Overview of glaucoma treatment options.

This information is for educational purposes and not a substitute for professional medical advice.