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Expert Definition

Understanding This Symptom

Medical Definition

Subject Matter Expert Verified

Sciatica is a condition characterized by pain radiating along the sciatic nerve, which runs from the lower back through the hips, buttocks, and down each leg.

It typically occurs when a herniated disc, bone spur, or spinal stenosis compresses part of the nerve, causing inflammation, numbness, and tingling that radiates from the lower back into the leg.

The most common levels involved are L4, L5, and S1 nerve roots, each affecting specific dermatomes and myotomes in the leg and foot.

Quick Facts

Expert-reviewed by medical professionals
Based on current medical research
Updated for 2026 standards

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Healthy State

What Optimal Health Looks Like

Understanding how your body functions when healthy helps identify dysfunction

In a healthy spine, the intervertebral discs maintain proper hydration and height, with intact annulus fibrosus rings protecting the nucleus pulposus.

The spinal canal and intervertebral foramina are spacious enough to allow the nerve roots to exit without compression.

The sciatic nerve, formed from L4, L5, S1, S2, and S3 nerve roots, passes freely through the pelvis and under the piriformis muscle without impingement.

Each nerve root innervates specific dermatomes (sensory zones) and myotomes (muscle groups).

Healthy Function

Your body is designed to maintain balance and self-regulate

Optimal Range
Development Process

How This Develops

1

Disc Herniation - nucleus pulposus material protrudes through a torn annulus fibrosus, compressing adjacent nerve roots at L

2

Foraminal Stenosis - narrowing of the intervertebral foramen due to disc bulge, bone spurs, or facet joint hypertrophy compresses exiting nerve roots; (

3

Central Canal Stenosis - narrowing of the spinal canal compresses multiple nerve roots; (

4

Spondylolisthesis - forward slippage of one vertebra over another narrows the nerve passage; (

5

Piriformis Syndrome - the piriformis muscle compresses the sciatic nerve in the buttock region; (

6

Nerve Root Inflammation - chemical irritation from inflammatory mediators from damaged discs; (

7

Radiculopathy - nerve root dysfunction causing sensory loss, weakness, and reflex changes along specific dermatomes and myotomes corresponding to the affected level

Understanding the mechanism helps us target the root cause rather than just treating symptoms.

Cost of Waiting

What Happens If Left Untreated

Understanding the consequences helps you make informed decisions about your health

Short-Term Consequences

Days to weeks

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Time Matters

Don't wait for symptoms to worsen. Early intervention leads to better outcomes.

Common Questions

Frequently Asked Questions

Expertise Behind This Guide

Evidence-Based Information

Dr. Hafeel Afsar, DHA Licensed Integrative Medicine

References & Further Reading

1. Valat JP, Genety J, Boureau F, et al. Sciatica. Joint Bone Spine. 2000;67(3):217-224.
2. Konstantinou K, Dunn KM. Sciatica: review of epidemiological studies and prevalence estimates. Spine (Phila Pa 1976). 2008;33(22):2464-2472. doi:10.1097/BRS.0b013e318183a4a2
3. Berry JA, Elia C, Singh H, et al. A Review of Lumbar Radiculopathy, Diagnosis, and Treatment. Cureus. 2019;11(10):e5934. doi:10.7759/cureus.5934
4. North American Spine Society. Diagnosis and Treatment of Lumbar Disc Herniation with Radiculopathy. Spine J. 2014;14(1):180-191.
5. Fairag M, Kurdi R, Al-Ghamdi S, et al. Epidemiology of Sciatica: Prevalence, Risk Factors and Association with Obesity and Sedentary Lifestyle. Open Access Maced J Med Sci. 2020;8(B):512-518.
6. Stafford MA, Peng P, Hill DA. Sciatica: a review of history, epidemiology, pathogenesis, and the role of epidural steroid injection in management. Br J Anaesth. 2007;99(4):461-473.

This information is for educational purposes and not a substitute for professional medical advice.