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Expert Definition

Understanding This Symptom

Medical Definition

Subject Matter Expert Verified

Sleep apnea is a serious sleep disorder characterized by repeated breathing interruptions during sleep, caused by airway collapse (obstructive sleep apnea/OSA) or failed brain signals (central sleep apnea/CSA).

These pauses in breathing, called apneas and hypopneas, reduce blood oxygen levels and disrupt sleep architecture, leading to excessive daytime sleepiness, cardiovascular strain, and increased risk of hypertension, heart disease, and stroke.

Quick Facts

Expert-reviewed by medical professionals
Based on current medical research
Updated for 2026 standards

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Healthy State

What Optimal Health Looks Like

Understanding how your body functions when healthy helps identify dysfunction

During healthy sleep, the upper airway maintains patency through coordinated activation of the genioglossus and tensor palatini muscles, preventing collapse during inspiration.

Normal sleep architecture progresses through NREM stages 1-3 and REM sleep, with stable respiratory drive from the medulla and pons.

Blood oxygen saturation (SpO2) remains above 95%, carbon dioxide levels stay within normal limits, and the heart maintains steady rate variability without sympathetic surges.

The collapsible pharynx remains open through neuromuscular compensation, allowing uninterrupted breathing throughout all sleep stages.

Healthy Function

Your body is designed to maintain balance and self-regulate

Optimal Range
Development Process

How This Develops

1

Upper Airway Anatomy - a narrowed or collapsible pharynx due to obesity, enlarged tonsils, tongue size, or craniofacial structure predisposes to airway collapse; (

2

Neuromuscular Compromise - reduced genioglossus and dilator muscle activity during sleep fails to counteract negative intrathoracic pressure; (

3

Arousal Threshold - repeated microarousals from the brain fragment sleep without full awakening, preventing deep restorative sleep; (

4

Ventilatory Control Instability - unstable respiratory drive from the brainstem creates periodic breathing patterns; (

5

Obesity Hypoventilation - excess adipose tissue restricts diaphragmatic excursion and increases airway collapsibility; (

6

Nighttime Desaturation - recurrent hypoventilation causes oxygen desaturation events, triggering sympathetic nervous system activation and catecholamine surges; (

7

Systemic Inflammation - intermittent hypoxia-reperfusion injury elevates CRP, IL-

Understanding the mechanism helps us target the root cause rather than just treating symptoms.

Cost of Waiting

What Happens If Left Untreated

Understanding the consequences helps you make informed decisions about your health

Short-Term Consequences

Days to weeks

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Time Matters

Don't wait for symptoms to worsen. Early intervention leads to better outcomes.

Common Questions

Frequently Asked Questions

Expertise Behind This Guide

Evidence-Based Information

Dr. Hafeel Afsar, DHA Licensed Integrative Medicine practitioner with expertise in sleep disorders and respiratory medicine. Advanced training in comprehensive sleep medicine, functional approaches to OSA, and cardiovascular risk reduction. Specializes in identifying root causes of sleep-disordered breathing and developing personalized treatment protocols that address the whole person rather than just the symptom.

References & Further Reading

1. Peppard PE, Young T, Barnet JH, et al. Increased prevalence of sleep-disordered breathing in adults. Am J Epidemiol. 2013;177(9):1006-1014. doi:10.1093/aje/kws342
2. McEvoy RD, Antic NA, Heeley E, et al. CPAP versus supportive care for obstructive sleep apnea. N Engl J Med. 2016;375(10):919-931. doi:10.1056/NEJMoa1606599
3. Jordan AS, McSharry DG, Malhotra A. Adult obstructive sleep apnoea. Lancet. 2014;383(9918):736-747. doi:10.1016/S0140-6736(13)60734-5
4. Javaheri S, Barbe F, Campos-Rodriguez F, et al. Sleep Apnea: Types, Mechanisms, and Clinical Importance. J Am Coll Cardiol. 2017;69(7):841-858. doi:10.1016/j.jacc.2016.11.069
5. Veasey SC, Rosen IM. Obstructive Sleep Apnea in Adults. N Engl J Med. 2019;380(15):1442-1449. doi:10.1056/NEJMcp1816152

This information is for educational purposes and not a substitute for professional medical advice.